Steven J Cohen Selected Research

4- imino- 1,3- diazabicyclo(3.1.0)hexan- 2- one

1/2018	A Phase 2 Randomized, Double-Blind, Multicenter Trial of Imexon Plus Gemcitabine Versus Gemcitabine Plus Placebo in Patients With Metastatic Chemotherapy-naïve Pancreatic Adenocarcinoma.
7/2010	A phase I study of imexon plus gemcitabine as first-line therapy for advanced pancreatic cancer.

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Steven J Cohen Research Topics

Disease

44	Neoplasms (Cancer) 10/2021 - 07/2002
26	Adenocarcinoma 01/2022 - 04/2003
25	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021 - 01/2002
18	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 08/2005
9	Esophageal Neoplasms (Esophageal Cancer) 08/2017 - 07/2009
8	Carcinoma (Carcinomatosis) 01/2021 - 10/2007
6	Neoplasm Metastasis (Metastasis) 01/2017 - 07/2005
6	Rectal Neoplasms (Rectal Cancer) 01/2016 - 12/2005
4	Neutropenia 01/2019 - 04/2003
3	Vomiting 10/2020 - 04/2003
3	Pathologic Complete Response 06/2015 - 10/2007
3	Diarrhea 02/2008 - 07/2002
2	Colonic Neoplasms (Colon Cancer) 10/2021 - 06/2015
2	Nausea 10/2020 - 04/2003
2	Exanthema (Rash) 10/2020 - 04/2003
2	Cardiotoxicity 10/2013 - 07/2012
2	Neuroendocrine Tumors (Neuroendocrine Tumor) 12/2011 - 03/2011
2	Thrombocytopenia (Thrombopenia) 06/2011 - 04/2003
2	Circulating Neoplastic Cells 10/2007 - 07/2006
2	Fatigue 06/2004 - 04/2003
1	Margins of Excision 01/2022
1	Lymphatic Metastasis 10/2021
1	Obesity 01/2021
1	Non-alcoholic Fatty Liver Disease 01/2021
1	Hypertension (High Blood Pressure) 01/2021
1	Hyperlipidemias (Hyperlipidemia) 01/2021
1	Inflammation (Inflammations) 01/2019
1	Cachexia 01/2019
1	Radiation Pneumonitis 11/2016

Drug/Important Bio-Agent (IBA)

10	Gemcitabine FDA Link 10/2020 - 07/2010
8	Oxaliplatin (Eloxatin)FDA LinkGeneric 10/2016 - 07/2005
6	Capecitabine (Xeloda)FDA Link 01/2021 - 02/2008
6	Fluorouracil (Carac)FDA LinkGeneric 08/2017 - 07/2002
5	Irinotecan (Camptosar)FDA LinkGeneric 10/2017 - 06/2004
5	Bevacizumab (Avastin)FDA Link 01/2017 - 02/2011
5	ErbB Receptors (EGF Receptor)IBA 09/2014 - 08/2005
4	130-nm albumin-bound paclitaxelIBA 10/2020 - 04/2016
4	Leucovorin (Folinic Acid)FDA Link 10/2016 - 06/2012
3	EnzymesIBA 01/2021 - 04/2003
3	MucinsIBA 09/2015 - 03/2009
3	Pharmaceutical PreparationsIBA 06/2011 - 01/2002
3	Proteins (Proteins, Gene)FDA Link 08/2008 - 04/2003
2	Hemoglobins (Hemoglobin)IBA 01/2021 - 02/2017
2	AlbuminsIBA 01/2021 - 04/2015
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 10/2020 - 04/2015
2	4- imino- 1,3- diazabicyclo(3.1.0)hexan- 2- oneIBA 01/2018 - 07/2010
2	Carcinoembryonic AntigenIBA 10/2017 - 01/2017
2	Cell Adhesion MoleculesIBA 10/2017 - 03/2009
2	YttriumIBA 01/2017 - 09/2015
2	Cetuximab (Erbitux)FDA Link 10/2016 - 12/2012
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 04/2016 - 10/2014
2	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA 09/2015 - 06/2011
2	Bortezomib (Velcade)FDA Link 06/2014 - 02/2008
2	Proteasome InhibitorsIBA 06/2014 - 02/2008
2	Monoclonal AntibodiesIBA 04/2014 - 12/2010
2	Insulin (Novolin)FDA Link 10/2013 - 07/2009
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2012 - 02/2011
2	Peptides (Polypeptides)IBA 12/2011 - 03/2011
2	Biomarkers (Surrogate Marker)IBA 02/2011 - 03/2009
2	Glucose (Dextrose)FDA LinkGeneric 07/2009 - 05/2009
2	Farnesyltranstransferase (Farnesyltransferase)IBA 06/2004 - 04/2003
2	tipifarnib (R115777)IBA 06/2004 - 04/2003
1	25-hydroxyvitamin DIBA 10/2021
1	Vitamin D FDA LinkGeneric 10/2021
1	hydroxide ionIBA 10/2021
1	AdiponectinIBA 10/2021
1	Quinacrine (Mepacrine)IBA 01/2021
1	thiamine triphosphorate (TTP)IBA 01/2021
1	N-acetyltalosaminuronic acid (NAT)IBA 01/2021
1	Recombinant Fusion ProteinsIBA 10/2020
1	PlatinumIBA 01/2020
1	pembrolizumabIBA 01/2020
1	IsoenzymesIBA 01/2019
1	CytokinesIBA 01/2019
1	itacitinibIBA 01/2019
1	trifluridine tipiracil drug combinationIBA 12/2018
1	Immunoconjugates (Immunoconjugate)IBA 10/2017
1	labetuzumab govitecanIBA 10/2017
1	vandetanib (ZD6474)IBA 08/2017
1	Paclitaxel (Taxol)FDA LinkGeneric 08/2017
1	Carboplatin (JM8)FDA LinkGeneric 08/2017
1	Indicators and Reagents (Reagents)IBA 01/2017
1	taxaneIBA 11/2016
1	Epirubicin (Ellence)FDA LinkGeneric 10/2016
1	Cisplatin (Platino)FDA LinkGeneric 10/2016
1	olaparibIBA 02/2016

Therapy/Procedure

37	Therapeutics 01/2022 - 01/2002
21	Drug Therapy (Chemotherapy) 01/2021 - 11/2007
12	Radiotherapy 01/2018 - 08/2005
8	Neoadjuvant Therapy 01/2022 - 12/2005
5	Chemoradiotherapy 12/2012 - 10/2007
3	Esophagectomy 01/2016 - 12/2012
3	Pancreatectomy 12/2011 - 05/2008
2	Combination Drug Therapy (Combination Chemotherapy) 01/2020 - 06/2012
2	Microspheres (Microsphere) 12/2015 - 04/2015
2	Radioimmunotherapy 09/2015 - 06/2011
1	Adjuvant Chemotherapy 10/2021
1	Pancreaticoduodenectomy 01/2021
1	Length of Stay 01/2021
1	Precision Medicine 10/2016